This is one of doTERRA’s most popular oil blends and is known as the protective blend to help protect the immune system. This oil contains a blend of five essential oils, including:

  • Wild orange (Citrus sinensis)
  • Clove bud (Eugenia caryophyllata)
  • Cinnamon bark (Cinnamomum zeylanicum)
  • Eucalyptus  (Eucalyptus globulus)
  • Rosemary (Rosmarinus officinalis)

What are the benefits of On Guard? According to doTERRA, On Guard can support healthy immune and cardiovascular function.

The company also claims that On Guard promotes healthy circulation when ingested and gives off an energising scent when it is diffused in the air. Once you have a diffuser you will never look back and wonder how you survived without one! I use mine everyday and can change the essential oils to what kind of mood you want to create. Additionally, you can use the oil blend as a natural household surface cleaner.

What does Science say?

Although studies suggest some benefits to using On Guard, research is limited and not conclusive. However I have personally found that it has kept many a bug and purified the air well. A 2017 study, which was funded by doTERRA and conducted by doTERRA employees, found that On Guard reduced inflammatory markers in human cells. It also indicated that the oil blend may promote wound healing and immune function.

According to a 2010 study, the On Guard blend may be effective in helping treat the influenza virus. The study found that the oil reduce the flu virus in in vitro in canine kidney cells that were infected. These cells, called MDCK cells, are commonly used in flu research because of their susceptibility to the virus. They also discovered that the oil may prevent this virus from producing as many viral proteins and being able to replicate as strongly.

Studies of the individual essential oils in the On Guard blend also suggest some benefits. A research review from 2019 indicated that eucalyptus essential oil may have immune-enhancing effects.

2016 study found that Cinnamon bark essential oil vapor had antimicrobial effects against viruses and bacteria common in respiratory infections. Clove and eucalyptus oils were also effective, but in liquid form.

According to doTERRA, there are four primary ways to use the On Guard blend:

  • ingesting it
  • diffusing it into the air for aromatherapy purposes
  • applying it on the skin
  • using it on surfaces as a household cleaner

To ingest On Guard, doTERRA recommends putting three to four drops into a veggie capsule or soaking apple slices in water with two to three drops of the oil. You could also put a drop in a teaspoon of honey and ingest it that way.

Please note that The National Association for Holistic Aromatherapy advises against ingesting essential oils, so please take precaution or seek medical expertise.

If you would like to diffuse On Guard, you can add 3 – 4 drops into your diffuser’s liquid base. The oil will then diffuse into the air and create a beautiful aroma. When you apply the essential oils to your skin, be sure to dilute one to two drops of the oil blend in a base, such as coconut oil.

The first time you use it, check for any skin sensitivity by putting diluted On Guard on a small area of skin for a patch test. Use a 1:30 dilution ratio — one drop of On Guard to 30 drops of a base oil — for the test.

If you notice any irritation or inflammation, wash the area and discontinue use. If you don’t experience any discomfort after 24 hours, it’s likely fine to apply to a larger area.

To use the oil blend as a cleaner, add the desired amount of oil to water, and spray the mixture on surfaces.

On Guard may lead to skin sensitivity. Avoid direct sunlight or UV rays for up to 12 hours after using the product on your skin.

Avoid using On Guard on any sensitive areas on the body, such as the eyes, inside of the ears, genital areas, irritated skin, or rashes.

Breathing in the oil may carry risks. A 2017 studyTrusted Source found that inhaling eucalyptus oil, one of the ingredients in the On Guard blend, may be linked to seizures in some people.

Children, older adults, women who are pregnant, and women who are breastfeeding shouldn’t use this essential oil blend without first consulting their medical provider.

If you’re looking for ways to protect yourself or your family from getting sick, there are a few other things you can do to help support your immune system:

Get enough sleep

Sleep is very important to help your immune system function properly.

2015 research review suggested that being sleep deprived can weaken immunity, potentially increasing inflammation and the chance of infection.

Skimping on sleep can significantly affect your overall health. So get your Zzz’s and make sure your kids get plenty of sleep as well.


research review from 2016 Trusted Source found that mindfulness meditation, which focuses on being present and aware, may help strengthen the immune system.

Specifically, it may be associated with reduced inflammation and mechanisms that protect against cell aging. Still, more research is needed on the effects of meditation on immune function.

Meditation may also help you sleep better, making it a win-win.


According to research from 2018, regular exercise may boost your immune system and lower your risk of chronic disease and infections.

For an even better pick-me-up, get your exercise outside for fresh air and vitamin D, which research indicates may be vital for immune function.

If you would like to try this oil or interested in purchasing this and/or other oils, please feel free to contact me via email/text/phone!